| Game # | Date | Time | Away | Home | Score | Record | Home | Away | Last 10 |
| 1 | 10/11/23 | 6:00PM | Montreal Canadiens | Toronto Maple Leafs | 5-6 (SOW) | 1-0-0 | 1-0-0 | 0-0-0 | 1-0-0 |
| 2 | 10/14/23 | 6:00PM | Minnesota Wild | Toronto Maple Leafs | 4-7 (W) | 2-0-0 | 2-0-0 | 0-0-0 | 2-0-0 |
| 3 | 10/16/23 | 6:00PM | Chicago Blackhawks | Toronto Maple Leafs | 4-1 (L) | 2-1-0 | 2-1-0 | 0-0-0 | 2-1-0 |
| 4 | 10/19/23 | 6:00PM | Toronto Maple Leafs | Florida Panthers | 1-3 (L) | 2-2-0 | 2-1-0 | 0-1-0 | 2-2-0 |
| 5 | 10/21/23 | 6:00PM | Toronto Maple Leafs | Tampa Bay Lightning | 4-3 (OTW) | 3-2-0 | 2-1-0 | 1-1-0 | 3-2-0 |
| 6 | 10/24/23 | 5:00PM | Toronto Maple Leafs | Washington Capitals | 4-1 (W) | 4-2-0 | 2-1-0 | 2-1-0 | 4-2-0 |
| 7 | 10/26/23 | 7:00PM | Toronto Maple Leafs | Dallas Stars | 4-1 (W) | 5-2-0 | 2-1-0 | 3-1-0 | 5-2-0 |
| 8 | 10/28/23 | 6:00PM | Toronto Maple Leafs | Nashville Predators | 2-3 (OTL) | 5-2-1 | 2-1-0 | 3-1-1 | 5-2-1 |
| 9 | 10/31/23 | 7:00PM | Los Angeles Kings | Toronto Maple Leafs | 4-1 (L) | 5-3-1 | 2-2-0 | 3-1-1 | 5-3-1 |
| 10 | 11/02/23 | 6:30PM | Toronto Maple Leafs | Boston Bruins | 2-3 (SOL) | 5-3-2 | 2-2-0 | 3-1-2 | 5-3-2 |
| Game # | Date | Time | Away | Home | Score | Record | Home | Away | Last 10 | 11 | 11/04/23 | 6:00PM | Buffalo Sabres | Toronto Maple Leafs | 6-4 (L) | 5-4-2 | 2-3-0 | 3-1-2 | 4-4-2 |
| 12 | 11/06/23 | 7:00PM | Tampa Bay Lightning | Toronto Maple Leafs | 5-6 (OTW) | 6-4-2 | 3-3-0 | 3-1-2 | 4-4-2 |
| 13 | 11/08/23 | 7:00PM | Ottawa Senators | Toronto Maple Leafs | 6-3 (L) | 6-5-2 | 3-4-0 | 3-1-2 | 4-4-2 |
| 14 | 11/10/23 | 7:00PM | Calgary Flames | Toronto Maple Leafs | 4-5 (SOW) | 7-5-2 | 4-4-0 | 3-1-2 | 5-3-2 |
| 15 | 11/11/23 | 7:00PM | Vancouver Canucks | Toronto Maple Leafs | 2-5 (W) | 8-5-2 | 5-4-0 | 3-1-2 | 5-3-2 |
| 16 | 11/17/23 | 2:00PM | Toronto Maple Leafs | Detroit Red Wings | 3-2 (W) | 9-5-2 | 5-4-0 | 4-1-2 | 5-3-2 |
| 17 | 11/19/23 | Toronto Maple Leafs | Minnesota Wild | 4-3 (OTW) | 10-5-2 | 5-4-0 | 5-1-2 | 5-3-2 | |
| 18 | 11/24/23 | 2:00PM | Toronto Maple Leafs | Chicago Blackhawks | 3-4 (OTL) | 10-5-3 | 5-4-0 | 5-1-3 | 5-3-2 |
| 19 | 11/25/23 | 7:00PM | Toronto Maple Leafs | Pittsburgh Penguins | 2-3 (L) | 10-6-3 | 5-4-0 | 5-2-3 | 5-3-2 |
| 20 | 11/28/23 | 7:00PM | Florida Panthers | Toronto Maple Leafs | 1-2 (SOW) | 11-6-3 | 6-4-0 | 5-2-3 | 6-3-1 |
| Game # | Date | Time | Away | Home | Score | Record | Home | Away | Last 10 | 21 | 11/30/23 | 7:00PM | Seattle Kraken | Toronto Maple Leafs | 3-4 (SOW) | 12-6-3 | 7-4-0 | 5-2-3 | 7-2-1 |
| 22 | 12/02/23 | 7:00PM | Boston Bruins | Toronto Maple Leafs | 4-3 (OTL) | 12-6-4 | 7-4-1 | 5-2-3 | 6-2-2 |
| 23 | 12/07/23 | 7:00PM | Toronto Maple Leafs | Ottawa Senators | 4-3 (W) | 13-6-4 | 7-4-1 | 6-2-3 | 7-1-2 |
| 24 | 12/09/23 | 7:00PM | Nashville Predators | Toronto Maple Leafs | 0-4 (W) | 14-6-4 | 8-4-1 | 6-2-3 | 7-1-2 |
| 25 | 12/11/23 | 7:00PM | Toronto Maple Leafs | New York Islanders | 3-4 (OTL) | 14-6-5 | 8-4-1 | 6-2-4 | 6-1-3 |
| 26 | 12/12/23 | 7:00PM | Toronto Maple Leafs | New York Rangers | 7-3 (W) | 15-6-5 | 8-4-1 | 7-2-4 | 6-1-3 |
| 27 | 12/14/23 | 7:00PM | Columbus Blue Jackets | Toronto Maple Leafs | 6-5 (OTL) | 15-6-6 | 8-4-2 | 7-2-4 | 5-1-4 |
| 28 | 12/16/23 | 7:00PM | Pittsburgh Penguins | Toronto Maple Leafs | 0-7 (W) | 16-6-6 | 9-4-2 | 7-2-4 | 6-1-3 |
| 29 | 12/19/23 | 7:00PM | New York Rangers | Toronto Maple Leafs | 5-2 (L) | 16-7-6 | 9-5-2 | 7-2-4 | 6-1-3 |
| 30 | 12/21/23 | 7:00PM | Toronto Maple Leafs | Buffalo Sabres | 3-9 (L) | 16-8-6 | 9-5-2 | 7-3-4 | 5-2-3 |
| Game # | Date | Time | Away | Home | Score | Record | Home | Away | Last 10 | 31 | 12/23/23 | 7:00PM | Toronto Maple Leafs | Columbus Blue Jackets | 4-1 (W) | 17-8-6 | 9-5-2 | 8-3-4 | 5-2-3 |
| 32 | 12/27/23 | 7:00PM | Ottawa Senators | Toronto Maple Leafs | 4-2 (L) | 17-9-6 | 9-6-2 | 8-3-4 | 5-3-2 |
| 33 | 12/29/23 | 7:00PM | Toronto Maple Leafs | Columbus Blue Jackets | 5-6 (OTL) | 17-9-7 | 9-6-2 | 8-3-5 | 4-3-3 |
| 34 | 12/30/23 | 7:00PM | Carolina Hurricanes | Toronto Maple Leafs | 3-2 (L) | 17-10-7 | 9-7-2 | 8-3-5 | 3-4-3 |
| 35 | 01/02/24 | 10:30PM | Toronto Maple Leafs | Los Angeles Kings | 3-0 (W) | 18-10-7 | 9-7-2 | 9-3-5 | 4-4-2 |
| 36 | 01/03/24 | 9:00PM | Toronto Maple Leafs | Anaheim Ducks | 2-1 (OTW) | 19-10-7 | 9-7-2 | 10-3-5 | 4-4-2 |
| 37 | 01/06/24 | 7:00PM | Toronto Maple Leafs | San Jose Sharks | 4-1 (W) | 20-10-7 | 9-7-2 | 11-3-5 | 5-4-1 |
| 38 | 01/09/24 | 7:00PM | San Jose Sharks | Toronto Maple Leafs | 1-7 (W) | 21-10-7 | 10-7-2 | 11-3-5 | 5-4-1 |
| 39 | 01/11/24 | 7:00PM | Toronto Maple Leafs | New York Islanders | 3-4 (OTL) | 21-10-8 | 10-7-2 | 11-3-6 | 5-3-2 |
| 40 | 01/13/24 | 7:00PM | Colorado Avalanche | Toronto Maple Leafs | 5-3 (L) | 21-11-8 | 10-8-2 | 11-3-6 | 5-3-2 |
| Game # | Date | Time | Away | Home | Score | Record | Home | Away | Last 10 | 41 | 01/14/24 | 7:30PM | Detroit Red Wings | Toronto Maple Leafs | 4-2 (L) | 21-12-8 | 10-9-2 | 11-3-6 | 4-4-2 |
| 42 | 01/16/24 | 9:00PM | Toronto Maple Leafs | Edmonton Oilers | 2-4 (L) | 21-13-8 | 10-9-2 | 11-4-6 | 4-4-2 |
| 43 | 01/18/24 | 9:00PM | Toronto Maple Leafs | Calgary Flames | 4-3 (W) | 22-13-8 | 10-9-2 | 12-4-6 | 5-4-1 |
| 44 | 01/20/24 | 7:00PM | Toronto Maple Leafs | Vancouver Canucks | 4-6 (L) | 22-14-8 | 10-9-2 | 12-5-6 | 5-4-1 |
| 45 | 01/21/24 | 9:00PM | Toronto Maple Leafs | Seattle Kraken | 3-1 (W) | 23-14-8 | 10-9-2 | 13-5-6 | 5-4-1 |
| 46 | 01/24/24 | 7:00PM | Winnipeg Jets | Toronto Maple Leafs | 0-1 (OTW) | 24-14-8 | 11-9-2 | 13-5-6 | 5-4-1 |
| 47 | 01/27/24 | 7:00PM | Toronto Maple Leafs | Winnipeg Jets | 4-2 (W) | 25-14-8 | 11-9-2 | 14-5-6 | 5-4-1 |
| 48 | 02/05/24 | 7:00PM | New York Islanders | Toronto Maple Leafs | 3-2 (L) | 25-15-8 | 11-10-2 | 14-5-6 | 4-5-1 |
| 49 | 02/07/24 | 7:00PM | Dallas Stars | Toronto Maple Leafs | 4-5 (W) | 26-15-8 | 12-10-2 | 14-5-6 | 5-5-0 |
| 50 | 02/10/24 | 7:00PM | Toronto Maple Leafs | Ottawa Senators | 3-5 (L) | 26-16-8 | 12-10-2 | 14-6-6 | 5-5-0 |
| Game # | Date | Time | Away | Home | Score | Record | Home | Away | Last 10 | 51 | 02/13/24 | 7:00PM | St. Louis Blues | Toronto Maple Leafs | 1-4 (W) | 27-16-8 | 13-10-2 | 14-6-6 | 6-4-0 |
| 52 | 02/15/24 | 7:00PM | Philadelphia Flyers | Toronto Maple Leafs | 3-4 (OTW) | 28-16-8 | 14-10-2 | 14-6-6 | 7-3-0 |
| 53 | 02/17/24 | 7:00PM | Anaheim Ducks | Toronto Maple Leafs | 2-9 (W) | 29-16-8 | 15-10-2 | 14-6-6 | 7-3-0 |
| 54 | 02/19/24 | 1:00PM | Toronto Maple Leafs | St. Louis Blues | 4-2 (W) | 30-16-8 | 15-10-2 | 15-6-6 | 8-2-0 |
| 55 | 02/21/24 | 10:00PM | Toronto Maple Leafs | 6-3 (W) | 31-16-8 | 15-10-2 | 16-6-6 | 8-2-0 | |
| 56 | 02/22/24 | 10:00PM | Toronto Maple Leafs | Vegas Golden Knights | 7-3 (W) | 32-16-8 | 15-10-2 | 17-6-6 | 8-2-0 |
| 57 | 02/24/24 | 7:00PM | Toronto Maple Leafs | Colorado Avalanche | 4-3 (W) | 33-16-8 | 15-10-2 | 18-6-6 | 8-2-0 |
| 58 | 02/27/24 | 7:00PM | Vegas Golden Knights | Toronto Maple Leafs | 6-2 (L) | 33-17-8 | 15-11-2 | 18-6-6 | 8-2-0 |
| 59 | 02/29/24 | 7:00PM | Toronto Maple Leafs | 2-4 (W) | 34-17-8 | 16-11-2 | 18-6-6 | 8-2-0 | |
| 60 | 03/02/24 | 7:00PM | New York Rangers | Toronto Maple Leafs | 3-4 (SOW) | 35-17-8 | 17-11-2 | 18-6-6 | 9-1-0 |
| Game # | Date | Time | Away | Home | Score | Record | Home | Away | Last 10 | 61 | 03/04/24 | 7:00PM | Boston Bruins | Toronto Maple Leafs | 4-1 (L) | 35-18-8 | 17-12-2 | 18-6-6 | 8-2-0 |
| 62 | 03/06/24 | 7:00PM | Buffalo Sabres | Toronto Maple Leafs | 1-2 (OTW) | 36-18-8 | 18-12-2 | 18-6-6 | 8-2-0 |
| 63 | 03/07/24 | 7:00PM | Toronto Maple Leafs | Boston Bruins | 1-4 (L) | 36-19-8 | 18-12-2 | 18-7-6 | 7-3-0 |
| 64 | 03/09/24 | 7:00PM | Toronto Maple Leafs | Montreal Canadiens | 3-2 (W) | 37-19-8 | 18-12-2 | 19-7-6 | 7-3-0 |
| 65 | 03/14/24 | 6:30PM | Toronto Maple Leafs | Philadelphia Flyers | 6-2 (W) | 38-19-8 | 18-12-2 | 20-7-6 | 7-3-0 |
| 66 | 03/16/24 | 6:00PM | Carolina Hurricanes | Toronto Maple Leafs | 5-4 (SOL) | 38-19-9 | 18-12-3 | 20-7-6 | 6-3-1 |
| 67 | 03/19/24 | 6:00PM | Toronto Maple Leafs | Philadelphia Flyers | 3-4 (L) | 38-20-9 | 18-12-3 | 20-8-6 | 5-4-1 |
| 68 | 03/20/24 | 6:30PM | Toronto Maple Leafs | Washington Capitals | 7-3 (W) | 39-20-9 | 18-12-3 | 21-8-6 | 6-3-1 |
| 69 | 03/23/24 | 6:00PM | Edmonton Oilers | Toronto Maple Leafs | 3-6 (W) | 40-20-9 | 19-12-3 | 21-8-6 | 6-3-1 |
| 70 | 03/24/24 | 5:00PM | Toronto Maple Leafs | Carolina Hurricanes | 1-2 (L) | 40-21-9 | 19-12-3 | 21-9-6 | 5-4-1 |
| Game # | Date | Time | Away | Home | Score | Record | Home | Away | Last 10 | 71 | 03/26/24 | 6:30PM | New Jersey Devils | Toronto Maple Leafs | 6-3 (L) | 40-22-9 | 19-13-3 | 21-9-6 | 5-4-1 |
| 72 | 03/28/24 | 6:00PM | Washington Capitals | Toronto Maple Leafs | 1-5 (W) | 41-22-9 | 20-13-3 | 21-9-6 | 5-4-1 |
| 73 | 03/30/24 | 6:00PM | Toronto Maple Leafs | Buffalo Sabres | 3-0 (W) | 42-22-9 | 20-13-3 | 22-9-6 | 6-3-1 |
| 74 | 04/01/24 | 6:00PM | Florida Panthers | Toronto Maple Leafs | 4-6 (W) | 43-22-9 | 21-13-3 | 22-9-6 | 6-3-1 |
| 75 | 04/03/24 | 6:00PM | Tampa Bay Lightning | Toronto Maple Leafs | 4-1 (L) | 43-23-9 | 21-14-3 | 22-9-6 | 5-4-1 |
| 76 | 04/06/24 | 6:00PM | Toronto Maple Leafs | Montreal Canadiens | 4-2 (W) | 44-23-9 | 21-14-3 | 23-9-6 | 6-4-0 |
| 77 | 04/08/24 | 6:00PM | Pittsburgh Penguins | Toronto Maple Leafs | 2-3 (OTW) | 45-23-9 | 22-14-3 | 23-9-6 | 7-3-0 |
| 78 | 04/09/24 | 6:00PM | Toronto Maple Leafs | New Jersey Devils | 5-2 (W) | 46-23-9 | 22-14-3 | 24-9-6 | 7-3-0 |
| 79 | 04/11/24 | 6:00PM | New Jersey Devils | Toronto Maple Leafs | 6-5 (L) | 46-24-9 | 22-15-3 | 24-9-6 | 6-4-0 |
| 80 | 04/13/24 | 6:00PM | Detroit Red Wings | Toronto Maple Leafs | 5-4 (OTL) | 46-24-10 | 22-15-4 | 24-9-6 | 6-3-1 |
| Game # | Date | Time | Away | Home | Score | Record | Home | Away | Last 10 | 81 | 04/16/24 | 6:30PM | Toronto Maple Leafs | Florida Panthers | 2-5 (L) | 46-25-10 | 22-15-4 | 24-10-6 | 6-3-1 |
| 82 | 04/17/24 | 6:00PM | Toronto Maple Leafs | Tampa Bay Lightning | 4-6 (L) | 46-26-10 | 22-15-4 | 24-11-6 | 5-4-1 |